Don't limit your applications by your protein tag!
Covalys' self-labeling tags give superior results for receptor internalization, binding studies, HTRF®, protein trafficking, and many other assays. All of this simply by changing labels on your tag without recloning.
Covalys is highly pleased to announce the introduction of a second protein tag for intracellular use - the CLIP-tag.This protein tag is closely related to the SNAP-tag, but it reacts with a different class of substrates.While the SNAP-tag reacts with benzylguanine derivatives, the CLIP-tag reacts with benzylcytosine derivatives.This difference in substrate recognition allows the simultaneous labeling of two different proteins in a cell or a cell population, including all the benefits already known for the SNAP-tag.A first set of substrates is available from April 2008 and Covalys will stepwise increase the number of products in the coming quarters. See also recent publications and the next issue of our quarterly newsletter.
