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Covalys' products offer distinct advantages in each experimental setting.
ACP-tag enables highly selective cell surface labeling. In addition, having no cysteines, ACP-tag should be useful for labeling secreted proteins with disulphide bridges such as antibodies.
SNAP-tag is used to study localization, translocation, and internalization of proteins in live cells; to covalently immobilize proteins direct from lysates on biosensors; for flow cytometry; to detect proteins in gels; for FRET-based interaction assays and binding assays in microtiter plate; and for many other applications. And still SNAP-tag's precision and versatility is far from being fully exploited. What's more, the same protein fusion can be used for all applications. Save cloning time and focus on what's important in your experiment.
Whether you use SNAP-tag or ACP-tag you can be sure of exquisite specificity coupled with robust covalent labeling.
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